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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
22.73
Human Site:
T249
Identified Species:
38.46
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
T249
L
L
G
S
G
K
V
T
D
R
K
A
L
S
E
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
T249
L
L
G
S
G
K
V
T
D
R
K
A
L
S
E
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
E303
L
Q
H
R
L
H
V
E
A
S
V
A
E
G
A
Dog
Lupus familis
XP_547295
1021
115999
T287
L
L
G
S
G
K
V
T
D
R
K
A
L
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
T249
L
L
G
S
G
K
V
T
D
R
K
A
L
S
E
Rat
Rattus norvegicus
O08874
985
112050
T251
L
L
G
S
G
K
V
T
D
R
K
A
L
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
E290
L
R
H
R
L
R
I
E
A
A
V
A
E
G
A
Chicken
Gallus gallus
XP_422357
1013
114806
T276
L
L
G
S
G
K
V
T
D
R
K
A
L
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
A241
L
L
G
S
G
K
L
A
E
K
R
A
H
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
R25
R
P
T
E
W
S
R
R
F
R
Q
D
E
A
A
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
E117
D
I
L
R
E
G
L
E
K
R
I
Q
E
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
L293
V
A
I
M
W
L
L
L
S
D
I
A
E
E
I
Red Bread Mold
Neurospora crassa
P87253
1142
127954
D261
I
L
A
V
K
D
V
D
H
A
P
L
G
R
F
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
13.3
100
N.A.
60
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
26.6
100
N.A.
86.6
N.A.
0
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
15
15
0
72
0
8
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
8
43
8
0
8
0
0
0
% D
% Glu:
0
0
0
8
8
0
0
22
8
0
0
0
36
8
50
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
50
0
50
8
0
0
0
0
0
0
8
15
0
% G
% His:
0
0
15
0
0
8
0
0
8
0
0
0
8
0
0
% H
% Ile:
8
8
8
0
0
0
8
0
0
0
15
0
0
0
8
% I
% Lys:
0
0
0
0
8
50
0
0
8
8
43
0
0
0
0
% K
% Leu:
65
58
8
0
15
8
22
8
0
0
0
8
43
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
8
8
0
22
0
8
8
8
0
58
8
0
0
8
0
% R
% Ser:
0
0
0
50
0
8
0
0
8
8
0
0
0
50
0
% S
% Thr:
0
0
8
0
0
0
0
43
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
58
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _